Creative Director, Neil Druckmann, just posted the story trailer for Uncharted 4: A Thief's End. In the post he also mentions how they're nearly done making the game which is great since the game comes out in less than 2 months!
Judging from just the trailer, the new characters seem memorable and overall the game looks promising. Neil even called it "the best trailer in Naughty Dog’s history."
Uncharted 4: A Thiefs End - Story Trailer | PS4
It looks like someone at Naughty Dog "borrowed" concept art from Assassin's Creed. The concept art was used as a painting in what looks like Drake's home. Maybe Drake likes to play Assassin's Creed when he's not hunting for treasure? The only disservice here would be that it was Assassin's Creed and not Tomb Raider. Anyhow, the trailer has now been updated and the concept art removed but here you can see how the painting looked in the trailer before and after:
This is the original concept art by Martin Deschambault who is a Senior Concept Artist at Ubisoft Montreal:
Naughty Dog issued a statement on their website apologizing: An update on the Uncharted 4: A Thief’s End Story Trailer
Release Date: April 26th, 2016
System: PlayStation 4